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Merck

ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

Synonyms:
CENTD2
Species:
Human ARAP1 (116985), Mouse Arap1 (69710), Rat Arap1 (361617), naked mole-rat Arap1 (101724042), cow ARAP1 (511889), Horse ARAP1 (100052506), domestic cat ARAP1 (101095128), domestic guinea pig Arap1 (100731432), sheep ARAP1 (101123146), dog ARAP1 (485207)
UniProtKB ID:
Q96P48, A3KLL7, B2RTS2, O94879, Q4LDD5, Q59FI7, Q6PHS3, Q8WU51
Gene ID:
  • Human(116985) Summary: The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
  • Mouse(69710) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
  • Rat(361617) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
  • naked mole-rat(101724042) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
  • cow(511889) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
  • Horse(100052506) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
  • domestic cat(101095128) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
  • domestic guinea pig(100731432) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
  • sheep(101123146) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
  • dog(485207) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2501827
Anti-ARAP1 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, mouse, pig, rat
Application
ELISA
immunocytochemistry
western blot