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45999

Sigma-Aldrich

Methyl acetate

suitable for HPLC, ≥99.8%

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About This Item

Linear Formula:
CH3COOCH3
CAS Number:
79-20-9
Molecular Weight:
74.08
Beilstein:
1736662
EC Number:
201-185-2
MDL number:
MFCD00008711
UNSPSC Code:
12190000
PubChem Substance ID:
329757046
NACRES:
NA.01

vapor density

2.55 (vs air)

Quality Level

100

vapor pressure

165 mmHg ( 20 °C)

Assay

≥99.8% (GC)
≥99.8%

form

liquid

autoignition temp.

936 °F

shelf life

limited shelf life, expiry date on the label

expl. lim.

16 %

technique(s)

HPLC: suitable

impurities

≤0.05% water

evapn. residue

≤0.001%

refractive index

n20/D 1.361 (lit.)
n20/D 1.362

bp

57-58 °C (lit.)

mp

−98 °C (lit.)

density

0.934 g/mL at 25 °C

solvent strength ε (Al2O3)

0.60

λ

1 cm path, H2O reference

UV absorption

λ: 255 nm Amax: 1.0
λ: 275 nm Amax: 0.1
λ: 300 nm Amax: 0.01

SMILES string

COC(C)=O

InChI

1S/C3H6O2/c1-3(4)5-2/h1-2H3

InChI key

KXKVLQRXCPHEJC-UHFFFAOYSA-N

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Application

  • Agglomeration of celecoxib by quasi-emulsion solvent diffusion method without stabilizer: effect of good solvent.: This research explored the agglomeration of celecoxib using the quasi-emulsion solvent diffusion method, highlighting the role of methyl acetate as a good solvent to improve particle size and distribution without the need for stabilizers (Maghsoodi & Nokhodchi, 2018).
  • Formulation and in vitro evaluation of ketoprofen in palm oil esters nanoemulsion for topical delivery.: The formulation and evaluation of ketoprofen in a nanoemulsion system for topical delivery were examined, with methyl acetate used as a solvent to enhance solubility and stability of the active ingredient (Sakeena et al., 2010).
  • Preparation of surfactant-free nanoparticles of methacrylic acid copolymers used for film coating.: This paper presented a method for preparing surfactant-free nanoparticles using methyl acetate as a solvent, emphasizing its role in the formation of uniform nanoparticle dispersions for coating applications (Nguyen et al., 2006).

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Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H319,H336

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

EUH066

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

8.6 °F - closed cup

Flash Point(C)

-13 °C - closed cup

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