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Key Documents

8.21027

Sigma-Aldrich

Phthaldialdehyde

for synthesis

Synonym(s):

Phthaldialdehyde, OPA

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About This Item

Linear Formula:
C6H4-1,2-(CHO)2
CAS Number:
Molecular Weight:
134.13
MDL number:
UNSPSC Code:
12352114
EC Index Number:
211-402-2
NACRES:
NA.22

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Quality Level

Assay

≥97.5% (GC)

form

solid

autoignition temp.

480 °C

potency

178 mg/kg LD50, oral (Rat)
>2000 mg/kg LD50, skin (Rat)

pH

7 (20 °C, 53 g/L in H2O)

bp

83-84 °C/1 hPa

mp

52-58 °C

transition temp

flash point 132 °C

solubility

53 g/L

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SAB4502936SAB4503801SAB3500372
conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

mol wt

antigen 76 kDa

mol wt

antigen 76 kDa

mol wt

antigen 76 kDa

mol wt

predicted mol wt 76 kDa

species reactivity

rat, human, mouse

species reactivity

mouse, human, rat

species reactivity

mouse, human, rat

species reactivity

human, mouse

Application


  • An investigation of o-phthaldialdehyde as a derivatization reagent and optimization of instrumental parameters for qualitative amino acid profiling via UPLC-UV Detailed examination of o-phthaldialdehyde′s efficiency in amino acid profiling to enhance diagnostic accuracies for metabolic diseases like AKU and PKU (A Aspö - 2023). Access the study.

  • Correlation of the Free Amino Nitrogen and Nitrogen by O-Phthaldialdehyde Methods in the Assay of Beer This research correlates nitrogen content measurements in beer using the o-phthaldialdehyde method, discussing its implications for brewing quality control (L Otama, S Tikanoja, H Kane, S Hartikainen, L Kaski - Date not specified). Access the study.

  • Turn-on fluorescence detection of glutathione based on o-phthaldialdehyde-assisted SiO2 particles Investigation into a novel fluorometric method for detecting glutathione in supplements using o-phthaldialdehyde and functionalized silica particles (P Nedeljko, M Turel, A Lobnik - 2018). Access the study.

  • Biochemical Measures of Neuropathy-Glutathione Assay (GSH) A study on the biochemical assessment of neuropathy by measuring glutathione levels using o-phthaldialdehyde in a methanol solution, emphasizing the methodology′s sensitivity and reliability (E Feldman - 2019). Access the study.

Analysis Note

Assay (GC, area%): ≥ 97.5 % (a/a)
Melting range (lower value): ≥ 52 °C
Melting range (upper value): ≤ 56 °C
Identity (IR): passes test

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

269.6 °F - closed cup

Flash Point(C)

132 °C - closed cup


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