- Copper-mediated N-cyclopropylation of azoles, amides, and sulfonamides by cyclopropylboronic acid.
Copper-mediated N-cyclopropylation of azoles, amides, and sulfonamides by cyclopropylboronic acid.
The Journal of organic chemistry (2008-07-10)
Sébastien Bénard, Luc Neuville, Jieping Zhu
PMID18610980
ABSTRACT
Reaction of azoles, amides, and sulfonamides in dichloroethane with readily available cyclopropylboronic acid in the presence of copper acetate and sodium carbonate afforded the N-cyclopropyl derivatives in good to excellent yields.
MATERIALS