sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

Natural product reports (2014-02-28)

Egor Geist, Andreas Kirschning, Thomas Schmidt

ABSTRACT

This Highlight covers the current status of relatively unexplored sp(3)-sp(3) cross-coupling reactions with particular focus on natural product and related syntheses.

MATERIALS

Product Number

Brand

Product Description

357634

Sigma-Aldrich

Nickel, wire, diam. 0.25 mm, ≥99.9%

203904

Sigma-Aldrich

Nickel, powder, <150 μm, 99.99% trace metals basis

510033

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2400, slurry, in H₂O, active catalyst

221678

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2800, slurry, in H₂O, active catalyst

268283

Sigma-Aldrich

Nickel, powder, <1 μm, 99.8% trace metals basis

267058

Sigma-Aldrich

Nickel, wire, diam. 0.5 mm, ≥99.99% trace metals basis

267007

Sigma-Aldrich

Nickel, foil, thickness 0.25 mm, 99.995% trace metals basis

268259

Sigma-Aldrich

Nickel, foil, thickness 0.125 mm, ≥99.9%

510068

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 3202, slurry, in H₂O, active catalyst

510041

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 4200, slurry, in H₂O, active catalyst

GF81268634

Nickel, wire reel, 200m, diameter 0.125mm, hard, 99.98%

GF67573389

Nickel, foil, 1m coil, thickness 0.20mm, coil width 1mm, annealed, 99%

GF80317605

Nickel, foil, 1m coil, thickness 0.025mm, coil width 600mm, as rolled, 99%

GF18961960

Nickel, tube, 200mm, outside diameter 1.3mm, inside diameter 1.1mm, wall thickness 0.1mm, hard, 99.5%

GF07420889

Nickel, tube, 100mm, outside diameter 3.6mm, inside diameter 3.5mm, wall thickness 0.05mm, hard, 99.5%

GF05063082

Nickel, foil, 25mm disks, thickness 0.075mm, annealed, 99%

GF96107542

Nickel, tube, 100mm, outside diameter 5.5mm, inside diameter 5mm, wall thickness 0.25mm, hard, 99.5%

GF53303396

Nickel, foil, 25mm disks, thickness 0.007mm, 99.95%

GF65873683

Nickel, foil, 25mm disks, thickness 0.025mm, 99.9%

GF95242989

Nickel, tube, 3mm, outside diameter 1.5mm, inside diameter 1.3mm, wall thickness 0.1mm, hard, 99.5%

GF66474636

Nickel, foil, 25mm disks, thickness 0.075mm, as rolled, 99.98%

GF20094803

Nickel, foil, 20m coil, thickness 0.05mm, coil width 2mm, annealed, 99%

GF78763236

Nickel, foil, 2m coil, thickness 0.125mm, annealed, 99%

GF97375832

Nickel, foil, 25x25mm, thickness 1.0mm, as rolled, 99.99+%

GF67542194

Nickel, foil, 10mm disks, thickness 0.0025mm, 99.95%

GF19140342

Nickel, foil, 150x150mm, thickness 0.25mm, annealed, 99.98%

GF17533997

Nickel, wire reel, 100m, diameter 0.5mm, annealed, 99%

GF58972753

Nickel, foil, 0.5m coil, thickness 0.015mm, 99.9%

GF00207638

Nickel, wire reel, 0.2m, diameter 1.0mm, as drawn, 99.99+%

GF48314763

Nickel, foil, 4mm disks, thickness 0.015mm, 99.9%