- Enantioselective synthesis of 1,2,4-triazolines by chiral iron(II)-complex catalyzed cyclization of α-isocyano esters and azodicarboxylates.
Enantioselective synthesis of 1,2,4-triazolines by chiral iron(II)-complex catalyzed cyclization of α-isocyano esters and azodicarboxylates.
Chemical communications (Cambridge, England) (2013-02-21)
Min Wang, Xiaohua Liu, Peng He, Lili Lin, Xiaoming Feng
PMID23423581
ABSTRACT
Enantioselective cyclization of α-isocyano esters with azodicarboxylates catalyzed by Fe(II)-N,N'-dioxide complexes has been developed. Under mild conditions, a variety of 1,2,4-triazoline derivatives was obtained in high yields and enantioselectivities.
MATERIALS