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Merck

Synthesis and antiviral activity of novel aza-acyclonucleosides.

Nucleosides & nucleotides (1999-03-06)
S C Bergmeier, S L Fundy, J C Drach
ABSTRACT

We have prepared a series of novel aza-acyclonucleosides as potential antiviral agents. These compounds were prepared from diethanolamine and the desired purine or pyrimidine base via a Mitsunobu coupling. No antiviral activity was observed against either HSV-1 or HCMV.