- oqxAB encoding a multidrug efflux pump in human clinical isolates of Enterobacteriaceae.
oqxAB encoding a multidrug efflux pump in human clinical isolates of Enterobacteriaceae.
Antimicrobial agents and chemotherapy (2009-06-17)
Hong Bin Kim, Minghua Wang, Chi Hye Park, Eui-Chong Kim, George A Jacoby, David C Hooper
PMID19528276
ABSTRACT
The genes for multidrug efflux pump OqxAB, which is active on fluoroquinolones, were found in human clinical isolates on a plasmid in Escherichia coli and on the chromosome of Klebsiella pneumoniae. IS26-like sequences flanked the plasmid-mediated oqxAB genes, suggesting that they had been mobilized as part of a composite transposon.