301310
2-Ethyl-2-thiopseudourea hydrobromide
98%
Synonym(s):
S-Ethylisothiourea hydrobromide
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All Photos(3)
About This Item
Linear Formula:
C2H5SC(=NH)NH2 · HBr
CAS Number:
Molecular Weight:
185.09
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
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Assay
98%
form
powder or crystals
mp
88-90 °C (lit.)
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
Br.CCSC(N)=N
InChI
1S/C3H8N2S.BrH/c1-2-6-3(4)5;/h2H2,1H3,(H3,4,5);1H
InChI key
SWXXKWPYNMZFTE-UHFFFAOYSA-N
Application
Reagent used in the synthesis of pyrimidines.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Claus Martin et al.
Cardiovascular research, 74(1), 46-55 (2007-01-30)
Nitric oxide (NO) synthesis by NO synthases (NOS) requires oxygen. However, although counterintuitive, NO synthesis is increased in ischemic myocardium. Accordingly, mechanisms independent of the NOS pathway have been suggested to contribute to NO synthesis during ischemia. NO initiates detrimental
A L Bardell et al.
The Journal of pharmacology and experimental therapeutics, 296(2), 252-259 (2001-02-13)
Experiments were performed to investigate whether nitric-oxide synthase (NOS) activity can be detected in vascular smooth muscle (VSM) from 12- to 14-week streptozotocin (STZ)-diabetic rats. Concentration-response curves to norepinephrine (NE) of superior mesenteric arteries from diabetic and age- and gender-matched
Barbara T Alexander et al.
Hypertension (Dallas, Tex. : 1979), 39(2 Pt 2), 586-590 (2002-03-08)
Acute, nonselective nitric oxide synthase inhibition in the pregnant rat decreases glomerular filtration rate and renal plasma flow, suggesting a role for nitric oxide in mediating renal vasodilation during pregnancy. As mid-gestation in the rat is associated with a significant
E Alhan et al.
The European journal of surgery = Acta chirurgica, 164(9), 697-702 (1998-09-05)
To investigate the effects of the constitutive nitric oxide (NO) synthase inhibitor NG-nitro-L-arginine methyl ester (L-Name) and the inducible NO synthase inhibitor amino ethyl-isothiourea (AE-ITU) on acute necrotising pancreatitis (ANP) in rats. Laboratory study. Medical school, Turkey. Morbidity, mortality, effects
W K Alderton et al.
The Biochemical journal, 332 ( Pt 1), 195-201 (1998-05-13)
Nitric oxide synthases (NOS) have a bidomain structure comprised of an N-terminal oxygenase domain and a C-terminal reductase domain. The oxygenase domain binds haem, (6R)-5,6,7,8-tetrahydro-l-biopterin (tetrahydrobiopterin) and arginine, is the site where nitric oxide synthesis takes place and contains determinants
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