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Merck

SMARCA2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

Synonyms:
BAF190, BRM, NCBRS, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p, hBRM, hSNF2a
Species:
UniProtKB ID:
Gene ID:
  • Human(6595) Summary: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jul 2008]
  • Mouse(67155) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  • Rat(361745) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  • Horse(100058279) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  • domestic cat(101083118) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  • chicken(396040) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  • Zebrafish(334032) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  • dog(476335) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  • Domestic Rabbit(100338619) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  • sheep(101110736) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  • naked mole-rat(101706423) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  • domestic guinea pig(100722639) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  • cow(540904) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SMARCA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-SMARCA2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Anti-Brm Antibody, clone 1H7A10, clone 1H7A10, from rat,
Species Reactivity
mouse
Application
immunohistochemistry
western blot
Monoclonal Anti-SMARCA2 antibody produced in mouse, clone 2D12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-SMARCA2 Antibody, clone 3E14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
SMARCA2 (1375-1511) human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SMARCA2,
Species
human
MISSION® esiRNA, targeting mouse Smarca2,
Species
mouse