Skip to Content
Merck

SIRT5

sirtuin 5

Synonyms:
SIR2L5
Species:
Human SIRT5 (23408), Mouse Sirt5 (68346), Rat Sirt5 (306840), Goat SIRT5 (100860989), cow SIRT5 (507347), naked mole-rat Sirt5 (101718891), dog SIRT5 (478726), domestic cat SIRT5 (101089862), chicken SIRT5 (420834), Zebrafish sirt5 (436878) ...More
UniProtKB ID:
Q9NXA8, B4DFM4, B4DYJ5, F5H5Z9, Q5T294, Q5T295, Q9Y6E6
Gene ID:
  • Human(23408) Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2010]
  • Mouse(68346) sirtuin 5
  • Rat(306840) sirtuin 5
  • Goat(100860989) sirtuin 5
  • cow(507347) sirtuin 5
  • naked mole-rat(101718891) sirtuin 5
  • dog(478726) sirtuin 5
  • domestic cat(101089862) sirtuin 5
  • chicken(420834) sirtuin 5
  • Zebrafish(436878) sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)
  • domestic guinea pig(100718110) sirtuin 5
  • sheep(101104099) sirtuin 5

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
RAB1702
Human Sirtuin 5 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
HPA021798
Anti-SIRT5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Species Reactivity
human
Application
immunohistochemistry
western blot
HPA022002
Anti-SIRT5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
HPA022992
Anti-SIRT5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab3,
Species Reactivity
human
Application
immunohistochemistry
western blot
AV32390
Anti-SIRT5 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
goat, guinea pig, human
Application
immunohistochemistry
western blot
SAB3500496
Anti-SIRT5 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
western blot

Proteins

Product Number
Description
Species
SRP5272
SIRT5, active, His tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
SRP0119
Sirtuin 5 human, recombinant, expressed in E. coli, ≥50% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
EHU132521
MISSION® esiRNA, targeting human SIRT5,
Species
human