RGS14
regulator of G-protein signaling 14
Synonyms:
Species:
Human RGS14 (10636), Mouse Rgs14 (51791), Rat Rgs14 (114705), dog RGS14 (489092), sheep RGS14 (101106525), domestic cat RGS14 (101099431), cow RGS14 (532605), domestic guinea pig Rgs14 (100728156), naked mole-rat Rgs14 (101722596), chicken RGS14 (769193)
UniProtKB ID:
Gene ID:
- Human(10636) Summary: This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
- Mouse(51791) regulator of G-protein signaling 14
- Rat(114705) regulator of G-protein signaling 14
- dog(489092) regulator of G-protein signaling 14
- sheep(101106525) regulator of G-protein signaling 14
- domestic cat(101099431) regulator of G-protein signaling 14
- cow(532605) regulator of G-protein signaling 14
- domestic guinea pig(100728156) regulator of G-protein signaling 14
- naked mole-rat(101722596) regulator of G-protein signaling 14
- chicken(769193) regulator of G-protein signaling 14
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RGS14 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-RGS14 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-RGS14 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot