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Merck

POLD4

polymerase (DNA-directed), delta 4, accessory subunit

Synonyms:
POLDS, p12
Species:
UniProtKB ID:
Gene ID:
  • Human(57804) Summary: This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
  • Mouse(69745) polymerase (DNA-directed), delta 4
  • Rat(361698) polymerase (DNA-directed), delta 4, accessory subunit
  • domestic guinea pig(100732830) polymerase (DNA-directed), delta 4, accessory subunit
  • sheep(101118743) polymerase (DNA-directed), delta 4, accessory subunit
  • domestic cat(101091308) polymerase (DNA-directed), delta 4, accessory subunit
  • cow(617899) polymerase (DNA-directed), delta 4
  • naked mole-rat(101706646) polymerase (DNA-directed), delta 4, accessory subunit
  • dog(611847) polymerase (DNA-directed), delta 4, accessory subunit
  • Thale Cress(837513) DNA polymerase delta subunit 4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-POLD4 antibody produced in mouse, clone 2B11, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-POLD4 antibody produced in mouse, clone 2C11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-POLD4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-POLD4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence

Small Molecule - Inhibitor

Product Number
Description
Species
Cytarabine, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Cytarabine, European Pharmacopoeia (EP) Reference Standard,
Species
human
Cytosine β-D-arabinofuranoside hydrochloride, crystalline,
Species
human
Cytarabine, United States Pharmacopeia (USP) Reference Standard,
Species
human
Cytarabine, British Pharmacopoeia (BP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human POLD4, AP003419.11,
Species
human