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Merck

ENPP1

ectonucleotide pyrophosphatase/phosphodiesterase 1

Synonyms:
ARHR2, M6S1, NPP1, NPPS, PC-1, PCA1, PDNP1
Species:
UniProtKB ID:
Gene ID:
  • Human(5167) Summary: This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. [provided by RefSeq, Jul 2008]
  • Mouse(18605) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • Rat(85496) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • domestic cat(101094350) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • sheep(101123048) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • chicken(426929) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • Domestic Rabbit(100009517) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • cow(615535) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • Horse(100073097) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • domestic guinea pig(100726931) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • naked mole-rat(101706464) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • Zebrafish(562399) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • dog(476153) ectonucleotide pyrophosphatase/phosphodiesterase 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ENPP1 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-ENPP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Enpp1,
Species
mouse
MISSION® esiRNA, targeting mouse Enpp1,
Species
mouse
MISSION® esiRNA, targeting human ENPP1,
Species
human