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Merck

CENPA

centromere protein A

Synonyms:
CENP-A, CenH3
Species:
UniProtKB ID:
Gene ID:
  • Human(1058) Summary: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(12615) centromere protein A
  • Rat(298850) centromere protein A
  • chicken(100113359) centromere protein A
  • dog(475692) centromere protein A
  • domestic cat(101082304) centromere protein A
  • cow(613898) centromere protein A
  • Zebrafish(100302659) histone H3-like centromeric protein A
  • naked mole-rat(101700835) centromere protein A
  • domestic guinea pig(100724949) centromere protein A
  • sheep(101110750) centromere protein A

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CENPA antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-CENP-A antibody produced in rabbit, ~2 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-Centromeric Protein A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry
Anti-CENP-A Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot
Anti-phospho-CENP-A (Ser7) Antibody, clone NL41, rabbit monoclonal, culture supernatant, clone NL41, Upstate®,
Species Reactivity
human
Application
immunocytochemistry
multiplexing

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Cenpa,
Species
mouse
MISSION® esiRNA, targeting human CENPA,
Species
human