Skip to Content
Merck

ABCC1

ATP-binding cassette, sub-family C (CFTR/MRP), member 1

Synonyms:
ABC29, ABCC, GS-X, MRP, MRP1
Species:
UniProtKB ID:
Gene ID:
  • Human(4363) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]
  • Mouse(17250) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Rat(24565) ATP-binding cassette, subfamily C (CFTR/MRP), member 1
  • naked mole-rat(101725452) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • sheep(101110991) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • domestic cat(101101279) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Horse(791240) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • chicken(395416) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Domestic Rabbit(100345841) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Zebrafish(100002010) ATP-binding cassette, sub-family C, member 1
  • cow(281588) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • domestic guinea pig(100734674) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • dog(403453) ATP-binding cassette, sub-family C (CFTR/MRP), member 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MRP1 antibody,Mouse monoclonal, clone QCRL-1, purified from hybridoma cell culture,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-MRP1 Antibody, clone QCRL-1, clone QCRL-1, Chemicon®, from mouse,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-MRP1/ABCC1 Antibody, clone 0J6M2, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
Anti-ABCC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-Multi-Drug Resistance Related Protein Antibody, clone MRPm6, culture supernatant, clone MRPm6, Chemicon®,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry

western blot

Cell Lines

Product Number
Description
Species
MRP1 Knockout Caco-2 Cells, one vial,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
Chloroquine diphosphate salt, powder or crystals, 98.5-101.0% (EP),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Abcc1,
Species
mouse
MISSION® esiRNA, targeting human ABCC1,
Species
human