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Key Documents

G7208

Sigma-Aldrich

Ethylene sulfite

98%

Synonym(s):

1,3,2-Dioxathiolan-2-oxide, Cyclic ethylene sulfite, ES, Glycol sulfite

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About This Item

Empirical Formula (Hill Notation):
C2H4O3S
CAS Number:
Molecular Weight:
108.12
Beilstein:
1237109
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

form

liquid

refractive index

n20/D 1.445 (lit.)

bp

159.1 °C (lit.)

density

1.426 g/mL at 25 °C (lit.)

SMILES string

O=S1OCCO1

InChI

1S/C2H4O3S/c3-6-4-1-2-5-6/h1-2H2

InChI key

WDXYVJKNSMILOQ-UHFFFAOYSA-N

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

197.1 °F

Flash Point(C)

91.7 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Joseph P O'Shea et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 207-216 (2015-07-29)
Novel formulations that overcome the solubility limitations of poorly water soluble drugs (PWSD) are becoming ever more critical to a drug development process inundated with these compounds. There is a clear need for developing bio-enabling formulation approaches to improve oral
Dharmendra K Yadav et al.
AAPS PharmSciTech, 16(4), 855-864 (2015-01-15)
The objective of this study was to develop novel docetaxel phospholipid nanoparticles (NDPNs) for intravenous administration. Modified solvent diffusion-evaporation method was adopted in the NDPN preparation. Central composite design (CCD) was employed in the optimization of the critical formulation factor
Hywel D Williams et al.
Journal of pharmaceutical sciences, 103(6), 1734-1746 (2014-04-18)
The current study determined the extent to which the desorption of lipid-based formulations (LBFs) from a mesoporous magnesium aluminometasilicate (Neusilin®-US2) carrier is governed by drug properties, LBF composition, and LBF-to-adsorbent ratio. A secondary objective was to evaluate the impact of
Hywel D Williams et al.
Journal of pharmaceutical sciences, 103(8), 2441-2455 (2014-07-06)
The Lipid Formulation Classification System Consortium looks to develop standardized in vitro tests and to generate much-needed performance criteria for lipid-based formulations (LBFs). This article highlights the value of performing a second, more stressful digestion test to identify LBFs near
Orlagh M Feeney et al.
Journal of controlled release : official journal of the Controlled Release Society, 192, 219-227 (2014-07-25)
For over 20years, stealth drug delivery has been synonymous with nanoparticulate formulations and intravenous dosing. The putative determinants of stealth in these applications are the molecular weight and packing density of a hydrophilic polymer (commonly poly(ethylene glycol) (PEG)) that forms

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