1667406

Timolol maleate

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Timolol maleate salt, S-(−)-1-(t-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol maleate salt, Timolol hydrogen maleate
• Empirical Formula (Hill Notation): C₁₃H₂₄N₄O₃S · C₄H₄O₄
• CAS Number: 26921-17-5
• Molecular Weight: 432.49
• NACRES: NA.24
• PubChem Substance ID: 329751325
• UNSPSC Code: 41116107
• MDL number: MFCD00058356

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: timolol
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: [H]\C(=C(/[H])C(O)=O)C(O)=O.CC(C)(C)NC[C@H](O)COc1nsnc1N2CCOCC2
• InChI: 1S/C13H24N4O3S.C4H4O4/c1-13(2,3)14-8-10(18)9-20-12-11(15-21-16-12)17-4-6-19-7-5-17;5-3(6)1-2-4(7)8/h10,14,18H,4-9H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t10-;/m0./s1
• InChI key: WLRMANUAADYWEA-NWASOUNVSA-N
• Gene Information: human ... ADRB1(153), ADRB2(154)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Timolol maleate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Dorzolamide Hydrochloride and Timolol Maleate Ophthalmic Solution
• Timolol Maleate
• Timolol Maleate Ophthalmic Solution
• Timolol Maleate Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H361
• pcodes: P280 - P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable