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T8691

Taurine

suitable for cell culture, BioXtra, meets USP testing specifications

Synonym(s):

2-Aminoethanesulfonic acid

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About This Item

Linear Formula:
NH2CH2CH2SO3H
CAS Number:
Molecular Weight:
125.15
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
203-483-8
MDL number:
Beilstein/REAXYS Number:
1751215
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Product Name

Taurine, suitable for cell culture, meets USP testing specifications

agency

meets USP testing specifications

Quality Level

product line

BioXtra

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

mp

>300 °C (lit.)

SMILES string

NCCS(O)(=O)=O

InChI

1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

InChI key

XOAAWQZATWQOTB-UHFFFAOYSA-N

Gene Information

rat ... Ppm1a(24666)

Application

Taurine has been used:
  • as a component of cardiomyocyte dissociation solution
  • as a supplement for modified synthetic oviduct fluid (m-SOF) medium to culture the presumptive zygotes
  • as a constituent of low Ca2+ solution employed in preparation of collagenase B solution for colony dissociation into single cells
  • to assess its effect on development of bovine embryos fertilized with different bull semen during in vitro fertilization
  • as a component of culture media for derivation of cornea organoids

Biochem/physiol Actions

Taurine is predominantly found in the retina and heart and is also found in the brain, intestine, skeletal muscles and kidneys. It controls the concentration of intracellular calcium, protects against ischemia-reperfusion injury and possesses blood pressure-lowering properties. Taurine also plays a vital role in bile formation and fat digestion. Deficiency of taurine is associated with development of anxiety, hyperactivity, epilepsy and depression.
Non-selective endogenous agonist at glycine receptors.
Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.

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1 of 1

This Item
T45718632993019
form

crystalline powder

form

crystalline powder

form

powder or crystals

form

-

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

UHPLC: suitable

technique(s)

gas chromatography (GC): suitable

product line

BioXtra

product line

-

product line

BioUltra

product line

TraceCERT®

impurities

endotoxin, tested

impurities

endotoxin, heavy metals, trace metals, tested

impurities

insoluble matter, passes filter test

impurities

-

color

white

color

-

color

colorless to white

color

-

Quality Level

200

Quality Level

400

Quality Level

200

Quality Level

300


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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Scalable expansion of human pluripotent stem cells in suspension culture
Zweigerdt R, et al.
Nature Protocols, 6(5), 689-689 (2011)
Patient-specific induced pluripotent stem cell models: generation and characterization of cardiac cells
Zanella F and Sheikh F
Methods in Molecular Biology, 147-162 (2014)
Cornea organoids from human induced pluripotent stem cells
Foster JW, et al.
Scientific Reports, 7 (2017)



Global Trade Item Number

SKUGTIN
T8691-1KG04061826759240
T8691-100G04061837379574
T8691-25G04061837379581

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. What are the recommendations for suspension and storage?

    1 answer
    1. This product is tested for solubility in water at 25 mg/mL. Other solvents have not been investigated. While this material is expected to be stable in solution, stability studies have not been performed. Other sources suggest that stock solutions are stable in aliquots at -20°C. Please see the link below to review a publication that may be helpful:
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128499/

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