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SML1707

Temoporfin

≥90% (HPLC)

Synonym(s):

3,3′,3′′,3′′′-(7,8-Dihydro-21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-phenol, 5,10,15,20-Tetra(m-hydroxyphenyl)chlorin

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$180.00
25 mg

Available to ship TODAYfromMILWAUKEE

$578.00

About This Item

Empirical Formula (Hill Notation):
C44H32N4O4
CAS Number:
Molecular Weight:
680.75
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥90% (HPLC)
Form:
powder

$180.00


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Quality Segment

assay

≥90% (HPLC)

form

powder

color

dark brown to black

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

−20°C

InChI

1S/C44H32N4O4/c49-29-9-1-5-25(21-29)41-33-13-15-35(45-33)42(26-6-2-10-30(50)22-26)37-17-19-39(47-37)44(28-8-4-12-32(52)24-28)40-20-18-38(48-40)43(36-16-14-34(41)46-36)27-7-3-11-31(51)23-27/h1-17,19,21-24,46-47,49-52H,18,20H2

InChI key

LYPFDBRUNKHDGX-UHFFFAOYSA-N

General description

Temoporfin/(tetra[m-hydroxyphenyl]chlorin, m-THPC), is a hydrophobic second-generation photosensitizer. It is used in the palliative treatment of patients with advanced head and neck cancer by photodynamic therapy.

Biochem/physiol Actions

Temoporfin is a photosensitizer for the photodynamic therapy.
Temoporfin is a photosensitizer for the photodynamic therapy. Temoporfin has been used clinically to treat advanced head and neck squamous cell carcinoma, and is being investigated for use in several other cancers.

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This Item
61356088071341492
form

powder

form

solid

form

crystals

form

solid

assay

≥90% (HPLC)

assay

≥90% (TLC)

assay

≥99.0% (HPLC)

assay

≥95% (TLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear (warmed)

solubility

water: 1 mg/mL

solubility

dichloromethane: soluble

solubility

water: soluble

color

dark brown to black

color

purple

color

-

color

dark brown


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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