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SML0468

Dorzolamide

≥98% (HPLC)

Synonym(s):

(4S,6S)-4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, 4S,6S-Dorzolamide, L-671,152, MK-507

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Size/SKUAvailabilityPrice
10 mg

Available to ship TODAYfromMILWAUKEE

$106.00
50 mg
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$433.00

About This Item

Empirical Formula (Hill Notation):
C10H16N2O4S3
CAS Number:
Molecular Weight:
324.44
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$106.00


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assay

≥98% (HPLC)

form

powder

optical activity

[α]/D -25 to -35°, c = 1 in methanol

color

white to beige

solubility

DMSO: 5 mg/mL (clear solution, warmed)

storage temp.

room temp

SMILES string

CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(cc12)S(N)(=O)=O

InChI

1S/C10H16N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8-/m0/s1

InChI key

IAVUPMFITXYVAF-XPUUQOCRSA-N

Gene Information

human ... CA2(760)

Biochem/physiol Actions

Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC50 value of 0.16 nM on human erythrocyte carbonic anhydrase II in vitro. It has been found to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension.
Dorzolamide is a potent carbonic anhydrase II inhibitor.

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SML0283SML0493SML1290
form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

−20°C

solubility

DMSO: 5 mg/mL (clear solution, warmed)

solubility

DMSO: ≥5 mg/mL (warmed)

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

DMSO: 5 mg/mL, clear (warmed)

color

white to beige

color

white to beige

color

white to beige

color

white to brown


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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