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SML0448

URB937

≥95% (HPLC)

Synonym(s):

Cyclohexylcarbamic acid 3′–carbamoyl–6–hydroxybiphenyl–3–yl ester

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$105.00
$89.25
25 mg

Available to ship TODAYfromMILWAUKEE

$408.00
$346.80

About This Item

Empirical Formula (Hill Notation):
C20H22N2O4
CAS Number:
Molecular Weight:
354.40
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥95% (HPLC)
Form:
powder (1:1 ratio of product to ethanol)

$89.25

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assay

≥95% (HPLC)

form

powder (1:1 ratio of product to ethanol)

color

white to beige

solubility

DMSO: 15 mg/mL, clear

storage temp.

−20°C

SMILES string

N(C3CCCCC3)C(=O)Oc1cc(c(cc1)O)c2cc(ccc2)C(=O)N

InChI

1S/C20H22N2O4/c21-19(24)14-6-4-5-13(11-14)17-12-16(9-10-18(17)23)26-20(25)22-15-7-2-1-3-8-15/h4-6,9-12,15,23H,1-3,7-8H2,(H2,21,24)(H,22,25)

InChI key

CMEQHOXCIGFZNJ-UHFFFAOYSA-N

Biochem/physiol Actions

URB937 is a fatty acid amide hydrolase (FAAH) inhibitor that is actively excluded from the CNS by the membrane transporter ABCG2. The ED50 for inhibition of FAAH activity in the brain is 200 times higher than inhibition of renal FAAH activity. In vivo administration of URB937 elevates anandamide levels in peripheral tissues, and attenuates acetic acid-induced writhing, hyperalgesia in a sciatic nerve ligation model, and pain and edema in carrageenan injected paws.
URB937 is a fatty acid amide hydrolase (FAAH) inhibitor.

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This Item
U4133B1686SML2345
assay

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

form

powder (1:1 ratio of product to ethanol)

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

DMSO: 15 mg/mL, clear

solubility

DMSO: soluble ~14 mg/mL

solubility

DMSO: >5 mg/mL

solubility

DMSO: 2 mg/mL, clear (warmed)

color

white to beige

color

white

color

dark red

color

white to beige


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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