RAB0325

Inhibin-B EIA Kit

for serum, plasma, culture supernatant and cell lysates

• NACRES: NA.32
• UNSPSC Code: 41123300

Properties

• species reactivity: rat, mouse, human
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable, enzyme immunoassay: suitable
• input: sample type plasma; sample type cell lysate; sample type serum; sample type culture supernatant(s)
• assay range: inter-assay cv: <15%; intra-assay cv: <10%; sensitivity: 2 pg/mL; standard curve range: 1-10000 pg/mL
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... INHBB(3625)

Description

General description

Inhibin-B (INHBB) is a heterodimeric glycoprotein with disulfide-linkage. It is produced by granulosa cells in the ovary.[1] The INHBB gene is mapped to human chromosome 2q14.2.[2] Inhibin-B inhibits follicle-stimulating hormone (FSH) secretion and synthesis.[1] It may serve in diagnosing testicular function[3] and as an indicator of Sertoli cell numbers and function.[4] Inhibin B may serve as a marker for spermatogenesis.[5]

The Inhibin B Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting Inhibin B peptide based on the principle of Competitive Enzyme Immunoassay. EIA-INB-1 targets the β B subunit, and therefore theoretically detects Activin B and Activin AB in addition to Inhibin B.

Immunogen

Inhibin-B, synthetic peptide

Application

Inhibin-B EIA Kit has been used in quantification of Inhibin-B using enzyme-linked immunosorbent assay (ELISA) in Zika virus-infected human Sertoli cells (HSerC)[5] and 8-week-old mice.[4]

Kit Components Also Available Separately

• RABHRP3

  HRP-Streptavidin

  SDS

Safety Information

• pictograms: GHS05
• signalword: Warning
• hcodes: H290
• pcodes: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Storage Class: 10 - Combustible liquids