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M4659

Milrinone

≥97% (TLC), powder, phosphodiesterase type III inhibitor

Synonym(s):

1,6-Dihydro-2-methyl-6-oxo-(3,4′-bipyridine)-5-carbonitrile

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Size/SKUAvailabilityPrice
10 mg

Estimated to ship onJune 18, 2026fromMILWAUKEE

$342.00
50 mg

Available to ship TODAYfromMILWAUKEE

$1,080.00

About This Item

Empirical Formula (Hill Notation):
C12H9N3O
CAS Number:
78415-72-2
Molecular Weight:
211.22
NACRES:
NA.77
PubChem Substance ID:
24278060
UNSPSC Code:
41106305
EC Number:
278-903-6
MDL number:
MFCD00133539
Assay:
≥97% (TLC)
Form:
powder

$342.00

Estimated to ship onJune 18, 2026Details

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Product Name

Milrinone, ≥97% (TLC), powder

Quality Segment

200

assay

≥97% (TLC)

form

powder

solubility

DMSO: >10 mg/mL, H2O: insoluble

originator

Sanofi Aventis

storage temp.

2-8°C

SMILES string

CC1=C(C=C(C#N)C(=O)N1)c2ccncc2

InChI

1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16)

InChI key

PZRHRDRVRGEVNW-UHFFFAOYSA-N

Gene Information

human ... PDE3A(5139), PDE3B(5140), PDE4B(5142), PDE5A(8654), PTPRA(5786)
rat ... Pde3a(50678)

Biochem/physiol Actions

Phosphodiesterase type III inhibitor; cAMP-specific, cGMP-inhibitable; potent cardiotonic, positive inotropic vasodilator.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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This Item
SML1184SML0645SML1209
Milrinone ≥97% (TLC), powder

Sigma-Aldrich

M4659

Milrinone

OF-1 ≥98% (HPLC)

Sigma-Aldrich

SML1184

OF-1

Iomazenil ≥98% (HPLC)

Sigma-Aldrich

SML0645

Iomazenil

OICR-9429 ≥98% (HPLC)

Sigma-Aldrich

SML1209

OICR-9429

assay

≥97% (TLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: >10 mg/mL, H2O: insoluble

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

DMSO: 10 mg/mL, clear

color

off-white

color

white to beige

color

white to beige

color

white to light brown

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pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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