G1049

Poly-L-γ-glutamic acid sodium salt

suitable for drug transporter assays, Mol wt ≥750,000

• Synonym(s): γ-PGA
• CAS Number: 208106-41-6
• MDL number: MFCD00081868
• NACRES: NA.26
• UNSPSC Code: 12352209

Properties

• Product Name: Poly-L-γ-glutamic acid sodium salt,
• form: powder
• Quality Segment: 100
• mol wt: ≥750,000
• technique(s): drug transporter assay: suitable
• color: white to off-white
• application(s): cell analysis
• storage temp.: −20°C

Description

Application

High molecular weight poly-γ-glutamic acid (γPGA) was found to increase levels of NK cell-mediated cytotoxicity and INF-γ secretion in C57BL/6 mice. Biodegradable γ-PGA nanoparticles have been evaluated for use as antigen delivery carriers and delivery of influenza virus hemagglutin (HA) vaccine. Additional life science applications for γ-PGA include uses in biodegradable fibers and nanofiber sheets, hydrogels, and cryoprotectants.

Other Notes

High molecular weight poly-γ-glutamic acid is a polymer of glutamic acid connected by amide linkages between α-amino and γ-carboxylic acid groups. γ-PGA is produced by fermentation in Bacillus species. The subunits are predominantly L-isomer.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable