17790

β-Eudesmol

≥90% (GC)

• Synonym(s): (2R,4aR,8aS)-Decahydro-8-methylene-α,α,4a-trimethyl-2-naphthylmethanol
• Empirical Formula (Hill Notation): C₁₅H₂₆O
• CAS Number: 473-15-4
• Molecular Weight: 222.37
• UNSPSC Code: 12352212
• NACRES: NA.25
• PubChem Substance ID: 57647672
• MDL number: MFCD00210502
• Beilstein/REAXYS Number: 5735560

Properties

• Quality Segment: 100
• assay: ≥90% (GC)
• form: powder
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: 2-8°C
• SMILES string: [H][C@@]12C[C@@H](CC[C@@]1(C)CCCC2=C)C(C)(C)O
• InChI: 1S/C15H26O/c1-11-6-5-8-15(4)9-7-12(10-13(11)15)14(2,3)16/h12-13,16H,1,5-10H2,2-4H3/t12-,13+,15-/m1/s1
• InChI key: BOPIMTNSYWYZOC-VNHYZAJKSA-N

Description

General description

β-Eudesmol is an aromatic, oxygenated sesquiterpene compound.[1] It is primarily observed in the bark of mangolia trees and can also be extracted from other medical herbs such as Cryptomeria japonica, Atractylodes lancea, Pterocarpus santalinus, Ginkgo biloba, and Nardostachys jatamansi.

Application

β-Eudesmol has been used:

• as a treatment to test its antioxidant, anti-inflammatory, cell preservation effects on human dermal fibroblasts (HDFs)
• as a reference standard to investigate if metabolically engineered E. coli extracted terpene synthase (Tps) genes encode for β-eudesmol synthase by using gas chromatography-mass spectrometry (GC/MS) analysis[2]
• to test its antiviral effects against herpes simplex virus type 1 (HSV-1)[3]
• to test its reversal effects of cocaine-induced planarian behavior[1]

Biochem/physiol Actions

β-Eudesmol has many pharmacological benefits. It is an active ingredient present in many essential oils, showing antioxidant and antimicrobial activities. β-Eudesmol elicits its antifungal and anti-wood-decay fungal activities in leaf essential oil of Litsea coreana [4] tree, and the twigs of Taiwania cryptomerioides trees[5] respectively. It suppresses tumor cell proliferation, growth, and migration of human tumor cells.[6][7] β-Eudesmol is known to have various protective effects on the nervous system.[1]

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)