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528175

Plasminogen, Human Plasma

Synonym(s):

Plasminogen, Human Plasma, Profibrinolysin, Plasma Trypsinogen

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Size/SKUAvailabilityPrice
120 U
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$483.00

About This Item

CAS Number:
UNSPSC Code:
12352202
NACRES:
NA.25
MDL number:
eCl@ss:
42030240
Specific activity:
≥120 units/mg protein
Assay:
≥95% (SDS-PAGE)
Biological source:
human plasma

$483.00


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biological source

human plasma

Quality Segment

description

Merck USA index - 14, 7521

assay

≥95% (SDS-PAGE)

form

lyophilized

specific activity

≥120 units/mg protein

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

water: soluble

shipped in

ambient

storage temp.

−20°C

General description

Native plasminogen from human plasma. Plasminogen is a single chain glycoprotein found in normal plasma at ~12 mg per deciliter, and is the inactive precursor of the serine protease plasmin.
Native plasminogen from human plasma. Single chain glycoprotein containing 790 amino acid residues. Found in normal plasma at about 12 mg/100 ml. Inactive precursor of the serine protease plasmin. Plasminogen is converted to the active protease by cleavage at Arg560.

Physical form

Lyophilized from 20 mM Tris-HCl, 2 mM EDTA, pH 7.5.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 2 months at -20°C.
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Other Notes

One unit is defined as the amount of enzyme that will hydrolyze 1 µmol of N-tosyl-Arg ethyl ester in 30 min at 37°C, pH 8.0.
Sun, Z., et al. 2002. Biochim. Biophys. Acta1596, 182.
Robbins, K.C., et al. 1967. J. Biol. Chem.242, 2333.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Toxicity: Irritant (B)

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This Item
52817810874477001528180
assay

≥95% (SDS-PAGE)

assay

-

assay

-

assay

-

biological source

human plasma

biological source

-

biological source

human serum

biological source

-

specific activity

≥120 units/mg protein

specific activity

7 units/mg protein

specific activity

~11 units/mg protein (activated with streptokinase at 37 °C and pH 7.4 with Chromozym PL as the substrate.)

specific activity

-

form

lyophilized

form

lyophilized

form

lyophilized

form

liquid

solubility

water: soluble

solubility

water: soluble

solubility

-

solubility

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

storage temp.

−70°C


Storage Class

11 - Combustible Solids

wgk

WGK 3



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Questions

  1. What is plasminogen solubility in water?

    1 answer
    1. This product is lyophilized from a solution containing 20 mM Tris-HCl, 2 mM EDTA, pH 7.5. The product may be reconstituted in water. Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 2 months at -20°C.

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