3542

Glutathione, Oxidized, Free Acid

≥95% (HPLC), Antioxidant, solid

• Synonym(s): Glutathione, Oxidized, Free Acid, Cyclic(γ-Glu-Cys-Gly)₂, GSSG
• Empirical Formula (Hill Notation): C₂₀H₃₂N₆O₁₂S₂
• CAS Number: 27025-41-8
• Molecular Weight: 612.63
• UNSPSC Code: 12352209
• NACRES: NA.25
• MDL number: MFCD00063106
• Assay: ≥95% (HPLC)
• Form: solid
• Storage condition: OK to freeze

Properties

• Product Name: Glutathione, Oxidized, Free Acid, Glutathione, Oxidized, Free Acid, CAS 27025-41-8, forms a "redox buffer" in physiological systems in the presence of reduced glutathione.
• Quality Segment: 200
• description: RTECS - MC0556500; Merck USA index - 14, 4475
• assay: ≥95% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• solubility: water: 1 mg/mL, DMF: 10 mg/mL, ethanol: 5 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: S(SCC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(=O)O)CC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(=O)O
• InChI: 1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)
• InChI key: YPZRWBKMTBYPTK-UHFFFAOYSA-N

Description

General description

Glutathione disulfide (GSSG) is the oxidized form of glutathione (GSH), an antioxidant containing cysteine, glycine, and glutamic acid. GSSG is composed of two reduced GSH molecules linked by a disulfide bond. GSSG plays an essential role in cellular redox balance, and protection against oxidative stress. The reduced glutathione-to-oxidized glutathione (GSH/GSSG) ratio serves as an indicator of oxidative stress. It is involved in various biochemical processes, including the regulation of immune function and metabolism.[1]

Features and Benefits

• Cell permeable: no
• Product does not compete with ATP
• Reversible: no

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable