The solution stability of this product has not been determined. However, various sources report that solutions in DMSO(fresh) are stable for 1 month at -20°C and 6 months at -80°C when stored in aliquots and protected from light.
802409
7-Azido-4-Methylcoumarin
97%
Synonym(s):
4-Methyl-7-azidocoumarin, 7-Azido-4-methyl-2H-1-benzopyran-2-one
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| Size/SKU | Availability | Price |
|---|---|---|
10 mg | Available to ship TODAYfromMILWAUKEE | $200.00 |
About This Item
Empirical Formula (Hill Notation):
C10H7N3O2
CAS Number:
Molecular Weight:
201.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352125
MDL number:
Assay:
97%
Form:
powder
$200.00
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Quality Segment
assay
97%
form
powder
mp
117.8 °C
SMILES string
CC1=CC(=O)Oc2cc(ccc12)N=[N+]=[N-]
InChI
1S/C10H7N3O2/c1-6-4-10(14)15-9-5-7(12-13-11)2-3-8(6)9/h2-5H,1H3
InChI key
HEKDKVLIMUWRRZ-UHFFFAOYSA-N
Application
7-Azido-4-methylcoumarin (AzMC) is a fluorogenic probe useful for the detection of hydrogen sulfide (H2S). The aromatic azide moiety is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with λex = 365nm and λem = 450nm. The probe can be used both to monitor enzymatic production of H2S in vitro[1] and also to visualize H2S in cells[2]. The probe is highly sensitive and selective for H2S, providing a linear detection range in vitro between 200nm – 100μM H2S with 10μM probe, and reacting selectively with H2S in the presence of mM concentrations of cysteine, homocysteine, glutathionine and many other common biological analytes.
Caution: Use of this product with DTT, TCEP and/or biological thiols >25mM should be avoided for maximum efficiency.
AzMC is readily soluble in DMSO.
Caution: Use of this product with DTT, TCEP and/or biological thiols >25mM should be avoided for maximum efficiency.
AzMC is readily soluble in DMSO.
1 of 1
This Item | |||
|---|---|---|---|
| assay 97% | assay ≥97.0% (GC) | assay 99% | assay ≥98.0% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| form powder | form solid | form - | form crystals |
| mp 117.8 °C | mp - | mp 230 °C (dec.) (lit.) | mp 230 °C (dec.) (lit.), 230-234 °C |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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