A9272

Adenosine 3′-monophosphate

from yeast

• Synonym(s): 3′-AMP, 3′-Adenylic acid
• Empirical Formula (Hill Notation): C₁₀H₁₄N₅O₇P
• CAS Number: 84-21-9
• Molecular Weight: 347.22
• Beilstein: 54478
• EC Number: 201-521-8
• MDL number: MFCD00005746
• UNSPSC Code: 41106305
• eCl@ss: 32160414
• PubChem Substance ID: 24891429
• NACRES: NA.51

Properties

• biological source: yeast
• Assay: ≥98% (HPLC)
• form: powder
• solubility: 1 N NH₄OH: 50 mg/mL, clear, colorless
• storage temp.: −20°C
• SMILES string: Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](OP(O)(O)=O)[C@H]3O
• InChI: 1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(17)7(4(1-16)21-10)22-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
• InChI key: LNQVTSROQXJCDD-KQYNXXCUSA-N

Description

Application

Adenosine 3′-monophosphate (3′-AMP) is a metabolite produced from hydrolysis of 2′,3′-cAMP by a family of metal-dependent phosphodiesterases. 3′-AMP inhibits proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. 2′,3′-cAMP and 3′-AMP represent a new unexplored pathway for adenosine-based cell regulation.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves