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80666

Sigma-Aldrich

Hexarelin

≥90% (HPLC)

Synonym(s):

HEX, L-Histidyl-2-methyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide, Examorelin

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About This Item

Empirical Formula (Hill Notation):
C47H58N12O6
CAS Number:
140703-51-1
Molecular Weight:
887.04
UNSPSC Code:
12352209
PubChem Substance ID:
329769022
NACRES:
NA.26

product name

Hexarelin, ≥90% (HPLC)

Assay

≥90% (HPLC)

form

powder

color

white

solubility

H2O: 1 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

C[C@H](NC(=O)[C@@H](Cc1c(C)[nH]c2ccccc12)NC(=O)[C@@H](N)Cc3cnc[nH]3)C(=O)N[C@@H](Cc4c[nH]c5ccccc45)C(=O)N[C@H](Cc6ccccc6)C(=O)N[C@@H](CCCCN)C(N)=O

InChI

1S/C47H58N12O6/c1-27-34(33-15-7-9-17-37(33)54-27)23-41(58-44(62)35(49)22-31-25-51-26-53-31)45(63)55-28(2)43(61)57-40(21-30-24-52-36-16-8-6-14-32(30)36)47(65)59-39(20-29-12-4-3-5-13-29)46(64)56-38(42(50)60)18-10-11-19-48/h3-9,12-17,24-26,28,35,38-41,52,54H,10-11,18-23,48-49H2,1-2H3,(H2,50,60)(H,51,53)(H,55,63)(H,56,64)(H,57,61)(H,58,62)(H,59,65)/t28-,35-,38-,39+,40-,41+/m0/s1

InChI key

RVWNMGKSNGWLOL-GIIHNPQRSA-N

Related Categories

Biochem/physiol Actions

Hexarelin (HEX), a ghrelin analogue, is a growth hormone secretagogue receptor agonist, a growth hormone releasing peptide. Hexarelin may be used as an internal standard in quantitative analysis (via chromatography etc.) of prohibited growth hormone enhancing drugs such as GHRP-2. The potential use of Hexarelin as a therapeutic has prompted research studies on its physiological effects in vitro and in vivo.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rosalyn Gloag et al.
Nature ecology & evolution, 1(1), 11-11 (2017-08-16)
Some invasive hymenopteran social insects found new populations with very few reproductive individuals. This is despite the high cost of founder effects for such insects, which generally require heterozygosity at a single locus-the complementary sex determiner, csd-to develop as females.
Erin M Euliano et al.
Scientific reports, 9(1), 11372-11372 (2019-08-08)
Reverse transcription polymerase chain reaction (RT-PCR) is the gold standard for the molecular diagnosis of many infectious diseases, including RNA viruses, but is generally limited to settings with access to trained personnel and laboratory resources. We have previously reported a
Olivier Humbert et al.
Science translational medicine, 11(503) (2019-08-02)
Reactivation of fetal hemoglobin (HbF) is being pursued as a treatment strategy for hemoglobinopathies. Here, we evaluated the therapeutic potential of hematopoietic stem and progenitor cells (HSPCs) edited with the CRISPR-Cas9 nuclease platform to recapitulate naturally occurring mutations identified in
T K Lehtonen et al.
Scientific reports, 8(1), 1166-1166 (2018-01-20)
Fine-scaled genetic structuring, as seen for example in many lacustrine fish, typically relates to the patterns of migration, habitat use, mating system or other ecological factors. Because the same processes can also affect the propensity of population differentiation and divergence
YuXia Huang et al.
Journal of the science of food and agriculture, 99(9), 4452-4459 (2019-03-14)
Diethylstilbestrol (DES) residues are harmful to human health because of their potential carcinogenic properties. Therefore, it is important to develop a fast and efficient pretreatment method to prevent their harmful effects on human health and the environment. In this paper
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