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  • BMP-induced reprogramming of the neural retina into retinal pigment epithelium requires Wnt signalling.

BMP-induced reprogramming of the neural retina into retinal pigment epithelium requires Wnt signalling.

Biology open (2017-05-27)
Jörg Steinfeld, Ichie Steinfeld, Alexander Bausch, Nicola Coronato, Meggi-Lee Hampel, Heike Depner, Paul G Layer, Astrid Vogel-Höpker
PMID28546339
ABSTRACT

In vertebrates, the retinal pigment epithelium (RPE) and photoreceptors of the neural retina (NR) comprise a functional unit required for vision. During vertebrate eye development, a conversion of the RPE into NR can be induced by growth factors