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1',2'-seco-dideoxynucleosides as potential anti-HIV agents.

Journal of medicinal chemistry (1989-01-01)
E Abushanab, M S Sarma
PMID2909746
ABSTRACT

1',2'-seco-2',3'-Dideoxycytidine (12), -guanosine (14), -adenosine (16), and -inosine (18) were prepared from (R)-benzylglycidol as potential anti-HIV agents. When compared to ddAdo in protecting ATH8 cells, they were found to be inactive.

MATERIALS
Product Number
Brand
Product Description
363529
Sigma-Aldrich
(R)-(−)-Glycidyl benzyl ether, 99%