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Merck

Visualizing nanoparticle mobility in liquid at atomic resolution.

Chemical communications (Cambridge, England) (2013-03-06)
Madeline J Dukes, Benjamin W Jacobs, David G Morgan, Harshad Hegde, Deborah F Kelly
ABSTRACT

Gold nanorods are widely known for their photothermal properties to treat solid tumors. Our work demonstrates the unrealized capacity to image these reagents in liquid at high resolution using Transmission Electron Microscopy (TEM). Here we perform the first atomic measurements of functionalized nanorods in solution while visualizing their dynamic behaviour with TEM.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Silicon nitride, nanopowder, <50 nm particle size (spherical), ≥98.5% trace metals basis
Sigma-Aldrich
Silicon nitride, powder, ≥99.9% trace metals basis
Sigma-Aldrich
Silicon nitride, predominantly β-phase, ≤10micron primary particle size
Sigma-Aldrich
Silicon nitride, predominantly α-phase, ≤10 micron