Skip to Content
Merck
  • Synthesis of 1-aminoisoquinolines via Rh(III)-catalyzed oxidative coupling.

Synthesis of 1-aminoisoquinolines via Rh(III)-catalyzed oxidative coupling.

Organic letters (2011-08-05)
Xiaohong Wei, Miao Zhao, Zhengyin Du, Xingwei Li
ABSTRACT

[RhCp*Cl(2)](2) can catalyze the oxidative coupling of N-aryl and N-alkyl benzamidines with alkynes to give N-substituted 1-aminoisoquinolines in high selectivity.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
1-Aminoisoquinoline, 99%