- Asymmetric synthesis of (+)-castanospermine through enol ether metathesis-hydroboration/oxidation.
Asymmetric synthesis of (+)-castanospermine through enol ether metathesis-hydroboration/oxidation.
Organic & biomolecular chemistry (2009-05-08)
Julien Ceccon, Grégory Danoun, Andrew E Greene, Jean-François Poisson
PMID19421437
ABSTRACT
An asymmetric synthesis of (+)-castanospermine is presented in which enol ether metathesis-hydroboration/oxidation is used for stereoselective installation of the trans-trans hydroxyl groups on the piperidine ring of the alkaloid.