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46960

Sigma-Aldrich

Fluorescein sodium salt

BioReagent, suitable for fluorescence

Synonym(s):

Acid Yellow 73, NaFl, Sodium fluorescein, Yellow No. 8, D&C;Yellow No. 8, NaFluo, Uranine

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About This Item

Empirical Formula (Hill Notation):
C20H10Na2O5
CAS Number:
518-47-8
Molecular Weight:
376.27
Colour Index Number:
45350
Beilstein:
3833041
EC Number:
208-253-0
MDL number:
MFCD00167039
UNSPSC Code:
12171500
PubChem Substance ID:
329757277
NACRES:
NA.32

product line

BioReagent

form

powder

technique(s)

titration: suitable

fluorescence

λex 460 nm; λem 515 nm(lit.)
λex 490 nm; λem 514 nm in 0.1 M Tris pH 8.0

suitability

suitable for fluorescence

SMILES string

[Na+].[Na+].[O-]c1ccc2c(Oc3cc([O-])ccc3C24OC(=O)c5ccccc45)c1

InChI

1S/C20H12O5.2Na/c21-11-5-7-15-17(9-11)24-18-10-12(22)6-8-16(18)20(15)14-4-2-1-3-13(14)19(23)25-20;;/h1-10,21-22H;;/q;2*+1/p-2

InChI key

RGPLGPBQJOQFJS-UHFFFAOYSA-L

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General description

Fluorescein Sodium Salt (FSS) is a xanthene dye having a polycrystalline structure with a monoclinic system. Fluorescein is a synthetic organic compound available as a dark orange/red powder soluble in water and alcohol.

Application

Fluorescein Sodium Salt (FSS) is used to conduct in-vivo skin studies.

Xanthene fluorophores, like Fluorescein Sodium Salt (FSS), are versatile compounds used across diverse fields of chemistry and life sciences.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

423.7 °F - Pensky-Martens closed cup

Flash Point(C)

217.6 °C - Pensky-Martens closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fluorescein United States Pharmacopeia (USP) Reference Standard

USP

1277004

Fluorescein

7-Diethylamino-4-methylcoumarin 99%

Sigma-Aldrich

D87759

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Joshua L Turnbull et al.
Journal of the American Chemical Society, 143(16), 6194-6201 (2021-04-03)
Xanthene fluorophores, like fluorescein, have been versatile molecules across diverse fields of chemistry and life sciences. Despite the ubiquity of 3-carboxy and 3-sulfonofluorescein for the last 150 years, to date, no reports of 3-phosphonofluorescein exist. Here, we report the synthesis
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Since proposed by Piekarski and Munro in 1977, load-induced fluid flow through the bone lacunar-canalicular system (LCS) has been accepted as critical for bone metabolism, mechanotransduction, and adaptation. However, direct unequivocal observation and quantification of load-induced fluid and solute convection
Sara Seabrooke et al.
American journal of physiology. Cell physiology, 305(5), C558-C567 (2013-06-28)
The blood-brain barrier (BBB) physiologically isolates the brain from the blood and, thus, plays a vital role in brain homeostasis. Ion transporters play a critical role in this process by effectively regulating access of chemicals to the brain. Organic anion-transporting
Tomoaki Murakami et al.
Ophthalmology, 120(12), 2596-2603 (2013-08-21)
To study the association between the fluorescence levels on fluorescein angiography images and the characteristics on spectral-domain optical coherence tomography (SD OCT) images in diabetic macular edema (DME). Retrospective, observational, cross-sectional study. One hundred sixty-seven consecutive eyes of 116 patients
Wee Yang Ng et al.
Biomicrofluidics, 3(2), 22405-22405 (2009-08-21)
This paper investigates the phenomenon of Faradaic charging in ac electrokinetics. Faradaic reactions were suggested as a key effect responsible for the reversal of pumping direction in ac micropumps. However, this hypothesis has yet to be proven convincingly and directly.
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