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Merck

XRCC6

X-ray repair complementing defective repair in Chinese hamster cells 6

Synonyms:
CTC75, CTCBF, G22P1, KU70, ML8, TLAA
Species:
UniProtKB ID:
Gene ID:
  • Human(2547) Summary: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
  • Mouse(14375) X-ray repair complementing defective repair in Chinese hamster cells 6
  • Rat(25019) X-ray repair complementing defective repair in Chinese hamster cells 6
  • domestic cat(101081395) X-ray repair complementing defective repair in Chinese hamster cells 6
  • chicken(395767) X-ray repair complementing defective repair in Chinese hamster cells 6
  • cow(510132) X-ray repair complementing defective repair in Chinese hamster cells 6
  • Domestic Rabbit(100351956) X-ray repair complementing defective repair in Chinese hamster cells 6
  • sheep(101112125) X-ray repair complementing defective repair in Chinese hamster cells 6
  • naked mole-rat(101703462) X-ray repair complementing defective repair in Chinese hamster cells 6
  • domestic guinea pig(100717277) X-ray repair complementing defective repair in Chinese hamster cells 6
  • Zebrafish(334488) X-ray repair complementing defective repair in Chinese hamster cells 6
  • dog(474485) X-ray repair complementing defective repair in Chinese hamster cells 6
  • Horse(100070684) X-ray repair complementing defective repair in Chinese hamster cells 6

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-XRCC6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry

western blot
Anti-Ku70 Protein Antibody, from rabbit,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-phospho-Ku70 (pSer5) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-XRCC6 antibody produced in mouse, clone 4C2-1A6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot