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Merck

UBE2B

ubiquitin-conjugating enzyme E2B

Synonyms:
E2-17kDa, HHR6B, HR6B, RAD6B, UBC2
Species:
UniProtKB ID:
Gene ID:
  • Human(7320) Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq, Jul 2008]
  • Mouse(22210) ubiquitin-conjugating enzyme E2B
  • Rat(81816) ubiquitin-conjugating enzyme E2B
  • dog(474683) ubiquitin-conjugating enzyme E2B
  • Zebrafish(437020) ubiquitin-conjugating enzyme E2B (RAD6 homolog)
  • domestic guinea pig(100713340) ubiquitin-conjugating enzyme E2B
  • Domestic Rabbit(100009132) ubiquitin-conjugating enzyme E2B
  • naked mole-rat(101706676) ubiquitin-conjugating enzyme E2B
  • domestic cat(101099525) ubiquitin-conjugating enzyme E2B
  • cow(512207) ubiquitin-conjugating enzyme E2B
  • sheep(100381250) ubiquitin-conjugating enzyme E2B

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