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Merck

TRAF4

TNF receptor-associated factor 4

Synonyms:
CART1, MLN62, RNF83
Species:
UniProtKB ID:
Gene ID:
  • Human(9618) Summary: This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
  • Mouse(22032) TNF receptor associated factor 4
  • Rat(303285) Tnf receptor associated factor 4
  • Horse(100072085) TNF receptor-associated factor 4
  • cow(781568) TNF receptor-associated factor 4
  • dog(100688511) TNF receptor-associated factor 4
  • domestic cat(101096365) TNF receptor-associated factor 4
  • chicken(417577) TNF receptor-associated factor 4
  • fruit fly(33638) TNF-receptor-associated factor 4
  • naked mole-rat(101716536) TNF receptor-associated factor 4
  • domestic guinea pig(100723177) TNF receptor-associated factor 4
  • sheep(101107451) TNF receptor-associated factor 4

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TRAF4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot

Proteins

Product Number
Description
Species
PrEST Antigen TRAF4, Prestige Antibodies® Powered by Atlas Antibodies, buffered aqueous solution,
Species
human