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Merck

TOPORS

topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase

Synonyms:
LUN, P53BP3, RP31, TP53BPL
Species:
Human TOPORS (10210), Mouse Topors (106021), Rat Topors (362501), naked mole-rat Topors (101717472), domestic cat TOPORS (101096178), Horse TOPORS (100053650), dog TOPORS (481577), sheep TOPORS (101113202), fruit fly Topors (37188), cow TOPORS (523321) ...More
UniProtKB ID:
Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9
Gene ID:
  • Human(10210) Summary: This gene encodes a nuclear protein which is serine and arginine rich, and contains a RING-type zinc finger domain. It is highly expressed in the testis, and functions as an ubiquitin-protein E3 ligase. Mutations in this gene are associated with retinitis pigmentosa type 31. Alternatively spliced transcript variants, encoding different isoforms, have been observed for this locus. [provided by RefSeq, Sep 2010]
  • Mouse(106021) topoisomerase I binding, arginine/serine-rich
  • Rat(362501) topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
  • naked mole-rat(101717472) topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
  • domestic cat(101096178) topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
  • Horse(100053650) topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
  • dog(481577) topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
  • sheep(101113202) topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
  • fruit fly(37188) Topoisomerase I-interacting protein
  • cow(523321) topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
  • domestic guinea pig(100718772) topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
  • chicken(427342) topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase

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