TMEM27
transmembrane protein 27
NX-17, NX17
Human TMEM27 (57393), Mouse Tmem27 (57394), Rat Tmem27 (57395), chicken TMEM27 (418622), domestic cat TMEM27 (101096034), dog TMEM27 (611445), domestic guinea pig Tmem27 (100712793), sheep TMEM27 (101123445), naked mole-rat Tmem27 (101700989), cow TMEM27 (513188)
- Human(57393) Summary: This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013]
- Mouse(57394) transmembrane protein 27
- Rat(57395) transmembrane protein 27
- chicken(418622) transmembrane protein 27
- domestic cat(101096034) transmembrane protein 27
- dog(611445) transmembrane protein 27
- domestic guinea pig(100712793) transmembrane protein 27
- sheep(101123445) transmembrane protein 27
- naked mole-rat(101700989) transmembrane protein 27
- cow(513188) transmembrane protein 27
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Antibodies
Anti-TMEM27 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
human
western blot