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Merck

TIGIT

T cell immunoreceptor with Ig and ITIM domains

Synonyms:
VSIG9, VSTM3, WUCAM
Species:
UniProtKB ID:
Gene ID:
  • Human(201633) Summary: This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]
  • Mouse(100043314) T cell immunoreceptor with Ig and ITIM domains
  • Rat(363784) T cell immunoreceptor with Ig and ITIM domains
  • naked mole-rat(101713509) T cell immunoreceptor with Ig and ITIM domains
  • domestic guinea pig(100716636) T cell immunoreceptor with Ig and ITIM domains
  • domestic cat(101098326) T cell immunoreceptor with Ig and ITIM domains
  • dog(487986) T cell immunoreceptor with Ig and ITIM domains
  • cow(100140801) T cell immunoreceptor with Ig and ITIM domains
  • sheep(101116533) T cell immunoreceptor with Ig and ITIM domains

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TIGIT Antibody, clone 1D20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-TIGIT (181-194) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
western blot
Anti-TIGIT Antibody, clone 4D4, ,
Species Reactivity
mouse
Application
ELISA
flow cytometry

inhibition assay

western blot