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Merck

TAF6

TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa

Synonyms:
MGC:8964, TAF(II)70, TAF(II)80, TAF2E, TAFII-70, TAFII-80, TAFII70, TAFII80, TAFII85
Species:
Human TAF6 (6878), Mouse Taf6 (21343), Rat Taf6 (288533), fruit fly Taf6 (40134), sheep TAF6 (101123178), domestic guinea pig Taf6 (100719322), Zebrafish taf6 (447818), domestic cat TAF6 (101088899), cow TAF6 (505638), chicken TAF6 (776310) ...More
UniProtKB ID:
P49848, A4D2B2, A4D2B3, B4DT11, D6W5U2, Q6AI29
Gene ID:
  • Human(6878) Summary: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
  • Mouse(21343) TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor
  • Rat(288533) TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor
  • fruit fly(40134) TBP-associated factor 6
  • sheep(101123178) TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
  • domestic guinea pig(100719322) TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
  • Zebrafish(447818) TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor
  • domestic cat(101088899) TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
  • cow(505638) TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
  • chicken(776310) TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
  • dog(489846) TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
  • naked mole-rat(101726460) TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
  • Horse(100067303) TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa

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