SUMF2
sulfatase modifying factor 2
Synonyms:
pFGE
Species:
Human SUMF2 (25870), Mouse Sumf2 (67902), Rat Sumf2 (360800), domestic guinea pig Sumf2 (100720126), naked mole-rat Sumf2 (101706082), chicken SUMF2 (417542), Zebrafish sumf2 (449807), dog SUMF2 (479701), domestic cat SUMF2 (101085769), cow SUMF2 (509497) ...More
UniProtKB ID:
Gene ID:
- Human(25870) Summary: The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- Mouse(67902) sulfatase modifying factor 2
- Rat(360800) sulfatase modifying factor 2
- domestic guinea pig(100720126) sulfatase modifying factor 2
- naked mole-rat(101706082) sulfatase modifying factor 2
- chicken(417542) sulfatase modifying factor 2
- Zebrafish(449807) sulfatase modifying factor 2
- dog(479701) sulfatase modifying factor 2
- domestic cat(101085769) sulfatase modifying factor 2
- cow(509497) sulfatase modifying factor 2
- sheep(101109064) sulfatase modifying factor 2
- Goat(100861033) sulfatase modifying factor 2
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