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Merck

STXBP2

syntaxin binding protein 2

Synonyms:
FHL5, Hunc18b, MUNC18-2, UNC18-2, UNC18B, pp10122
Species:
Human STXBP2 (6813), Mouse Stxbp2 (20911), Rat Stxbp2 (81804), domestic guinea pig Stxbp2 (100720057), naked mole-rat Stxbp2 (101702294), cow STXBP2 (515618), sheep STXBP2 (101102061), dog STXBP2 (403880), domestic cat STXBP2 (101096543), Zebrafish stxbp2 (406578)
UniProtKB ID:
Q15833, Q9BU65
Gene ID:
  • Human(6813) Summary: This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2013]
  • Mouse(20911) syntaxin binding protein 2
  • Rat(81804) syntaxin binding protein 2
  • domestic guinea pig(100720057) syntaxin binding protein 2
  • naked mole-rat(101702294) syntaxin binding protein 2
  • cow(515618) syntaxin binding protein 2
  • sheep(101102061) syntaxin binding protein 2
  • dog(403880) syntaxin binding protein 2
  • domestic cat(101096543) syntaxin binding protein 2
  • Zebrafish(406578) syntaxin binding protein 2

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Antibodies

Product Number
Description
Species Reactivity
Application
M4438
Anti-Munc-18 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
rat
Application
immunoprecipitation (IP)
western blot