SRF
serum response factor (c-fos serum response element-binding transcription factor)
Synonyms:
MCM1
Species:
Human SRF (6722), Mouse Srf (20807), Rat Srf (501099), fruit fly Srf (252723), chicken SRF (396103), domestic cat SRF (101085210), dog SRF (612861), cow SRF (533039), sheep SRF (101111402), domestic guinea pig Srf (100715998)
UniProtKB ID:
Gene ID:
- Human(6722) Summary: This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq, Jul 2008]
- Mouse(20807) serum response factor
- Rat(501099) serum response factor (c-fos serum response element-binding transcription factor)
- fruit fly(252723) Surf wings
- chicken(396103) serum response factor (c-fos serum response element-binding transcription factor)
- domestic cat(101085210) serum response factor (c-fos serum response element-binding transcription factor)
- dog(612861) serum response factor (c-fos serum response element-binding transcription factor)
- cow(533039) serum response factor (c-fos serum response element-binding transcription factor)
- sheep(101111402) serum response factor (c-fos serum response element-binding transcription factor)
- domestic guinea pig(100715998) serum response factor (c-fos serum response element-binding transcription factor)
- naked mole-rat(101719000) serum response factor (c-fos serum response element-binding transcription factor)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SRF Antibody, clone 2C5, ,
Species Reactivity
human, mouse
Application
immunohistochemistry
Anti-SRF antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SRF antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Product Number
Description
Species
C-fos, proto oncogene human, recombinant, expressed in insect cells, ≥70% (SDS-PAGE),
Species
human