SPTBN4
spectrin, beta, non-erythrocytic 4
Synonyms:
QV, SPNB4, SPTBN3
Species:
Human SPTBN4 (57731), Mouse Sptbn4 (80297), Rat Sptbn4 (308458), domestic guinea pig Sptbn4 (100724245), naked mole-rat Sptbn4 (101697752), domestic cat SPTBN4 (101088707), cow SPTBN4 (537578), sheep SPTBN4 (101120011), chicken SPTBN4 (430775), dog SPTBN4 (484499)
UniProtKB ID:
Gene ID:
- Human(57731) Summary: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein localizes to the nuclear matrix, PML nuclear bodies, and cytoplasmic vesicles. A highly similar gene in the mouse is required for localization of specific membrane proteins in polarized regions of neurons. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(80297) spectrin beta, non-erythrocytic 4
- Rat(308458) spectrin, beta, non-erythrocytic 4
- domestic guinea pig(100724245) spectrin, beta, non-erythrocytic 4
- naked mole-rat(101697752) spectrin, beta, non-erythrocytic 4
- domestic cat(101088707) spectrin, beta, non-erythrocytic 4
- cow(537578) spectrin, beta, non-erythrocytic 4
- sheep(101120011) spectrin, beta, non-erythrocytic 4
- chicken(430775) spectrin, beta, non-erythrocytic 4
- dog(484499) spectrin, beta, non-erythrocytic 4
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Spectrin antibody produced in rabbit, whole antiserum,
Species Reactivity
human
Application
western blot