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Merck

SIGLEC5

sialic acid binding Ig-like lectin 5

Synonyms:
CD170, CD33L2, OB-BP2, OBBP2, SIGLEC-5
Species:
Human SIGLEC5 (8778), Mouse Siglec5 (233186), Rat Siglec5 (292843), cow SIGLEC5 (100300478), dog SIGLEC5 (476396), naked mole-rat Siglec5 (101708758), domestic cat SIGLEC5 (101094223), domestic guinea pig Siglec5 (100736000)
UniProtKB ID:
O15389
Gene ID:
  • Human(8778) Summary: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]
  • Mouse(233186) sialic acid binding Ig-like lectin 5
  • Rat(292843) sialic acid binding Ig-like lectin 5
  • cow(100300478) sialic acid binding Ig-like lectin 5
  • dog(476396) sialic acid binding Ig-like lectin 5
  • naked mole-rat(101708758) sialic acid binding Ig-like lectin 5
  • domestic cat(101094223) sialic acid binding Ig-like lectin 5
  • domestic guinea pig(100736000) sialic acid binding Ig-like lectin 5

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ELISA

Product Number
Description
Species
RAB0433
Human Siglec-5 ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB1303597
ANTI-SIGLEC5 (N-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot