RFC5
replication factor C (activator 1) 5, 36.5kDa
Synonyms:
RFC36
Species:
Human RFC5 (5985), Mouse Rfc5 (72151), Rat Rfc5 (304528), domestic cat RFC5 (101092297), Zebrafish rfc5 (445385), naked mole-rat Rfc5 (101710167), sheep RFC5 (101109740), domestic guinea pig Rfc5 (100723132), Horse RFC5 (100054946), dog RFC5 (477499) ...More
UniProtKB ID:
Gene ID:
- Human(5985) Summary: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9. [provided by RefSeq, May 2011]
- Mouse(72151) replication factor C (activator 1) 5
- Rat(304528) replication factor C (activator 1) 5
- domestic cat(101092297) replication factor C (activator 1) 5, 36.5kDa
- Zebrafish(445385) replication factor C (activator 1) 5
- naked mole-rat(101710167) replication factor C (activator 1) 5, 36.5kDa
- sheep(101109740) replication factor C (activator 1) 5, 36.5kDa
- domestic guinea pig(100723132) replication factor C (activator 1) 5, 36.5kDa
- Horse(100054946) replication factor C (activator 1) 5, 36.5kDa
- dog(477499) replication factor C (activator 1) 5, 36.5kDa
- cow(508389) replication factor C (activator 1) 5, 36.5kDa
- Domestic Rabbit(100345366) replication factor C (activator 1) 5, 36.5kDa
- chicken(100859719) replication factor C (activator 1) 5, 36.5kDa
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.